Primary Sjögren’s syndrome presenting with hypokalemic periodic paralysis: A case series

Authors

  • Margi Dipakkumar Patel 3rd Year Postgraduate Resident, Department of General Medicine, Sumandeep Vidyapeeth, A Deemed-to-be University, Smt. B. K. Shah Medical Institute and Research Centre, Vadodara, Gujarat, India https://orcid.org/0009-0002-2364-3124
  • Naman Ashokbhai Popat 3rd Year Postgraduate Resident, Department of General Medicine, Sumandeep Vidyapeeth, A Deemed-to-be University, Smt. B. K. Shah Medical Institute and Research Centre, Vadodara, Gujarat, India https://orcid.org/0009-0001-4896-9967
  • Chiranjeev Dilipkumar Mehta 3rd Year Postgraduate Resident, Department of General Medicine, Sumandeep Vidyapeeth, A Deemed-to-be University, Smt. B. K. Shah Medical Institute and Research Centre, Vadodara, Gujarat, India https://orcid.org/0009-0006-9232-8717
  • Dharmendra J Vatsaraj Professor and Head, Department of General Medicine, Sumandeep Vidyapeeth, A Deemed-to-be University, Smt. B. K. Shah Medical Institute and Research Centre, Vadodara, Gujarat, India https://orcid.org/0009-0004-2259-4724

DOI:

https://doi.org/10.71152/ajms.v16i6.4508

Keywords:

Distal renal tubular acidosis; Hypokalemic paralysis; Sjögren’s syndrome; Tubulointerstitial nephritis

Abstract

Tubulointerstitial nephritis (TIN) is the primary renal involvement associated with primary Sjögren’s syndrome (pSS). We present a series of female patients with hypokalemic paralysis due to distal renal tubular acidosis. The patients received symptomatic treatment, including potassium supplementation, with favorable responses. The evidence suggests an underlying inflammatory mechanism that can lead to serious complications such as hypokalemic paralysis. Based on our findings, a combination of potassium supplementation and corticosteroid therapy is suggested for managing pSS-associated TIN.

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Published

2025-05-31

How to Cite

Margi Dipakkumar Patel, Naman Ashokbhai Popat, Chiranjeev Dilipkumar Mehta, & Dharmendra J Vatsaraj. (2025). Primary Sjögren’s syndrome presenting with hypokalemic periodic paralysis: A case series. Asian Journal of Medical Sciences, 16(6), 153–156. https://doi.org/10.71152/ajms.v16i6.4508

Issue

Vol. 16 No. 6 (2025)

Section

Case Series

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Copyright (c) 2025 Asian Journal of Medical Sciences

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